Testosterone therapy is all the rage Is it safeor effective? Center for Science in the Public Interest

Testosterone therapy is all the rage Is it safeor effective? Center for Science in the Public Interest

Most current data, including two reports in 2015, no longer supports a link between testosterone replacement and the development of 1) prostate cancer, 2) more aggressive prostate cancer, or 3) prostate cancer that returns after treatment. Nurses can also counsel patients on dosing and administration and assess treatment effectiveness. Both pharmacists and nurses must inform the prescriber of any concerns they may encounter, so open communication channels and shared decision-making among team members are vital. Monitoring of the patient by the interprofessional team will result in the best outcomes with the fewest adverse events. The clinical team needs to monitor patients receiving testosterone therapy regularly, and they should discontinue treatment for those who fail to follow up. Intramuscular injections of testosterone include testosterone enanthate and testosterone cypionate.

Here is how to take a cautious approach to testosterone therapy. People can testosterone raise liver enzymes; www.e-pol.it, take TRT orally, via intramuscular injections and implants or transdermal patches, mouth patches, and topical creams or gels. Severe lower urinary tract symptoms include urinary frequency and urgency.

Testosterone nasal spray also contains a type of gel but doesn’t carry the risk of transference. Instead, the medication is applied into the nose and absorbed there through the nasal lining. However, it requires more frequent application than any of the other medications. Depending on the cause and diagnosis, Dr. Muthigi treats low testosterone in a couple different ways, including lifestyle changes and medical supplementation. Individuals with osteoporosis or low trauma fracture history will undergo a bone density scan one to two years after the initiation of TRT therapy. Options available depend on the person’s medical needs and lifestyle/ People should discuss these with their healthcare practitioner prior to commencing treatment.

Although there are many supplements claiming to boost testosterone, these over-the-counter products do not contain testosterone and lack any peer reviewed evidence of effectiveness. Your doctor may order certain tests to check your body’s response to testosterone injection. Testosterone injection may cause the bones to mature more quickly than normal in children who receive the medication. This means that the children may stop growing sooner than expected and may have a shorter than expected adult height. The proposal was part of a collaboration between the VA Cooperative Studies Program, which is responsible for planning and conducting large clinical trials and epidemiological studies in VA, and the National Institute on Aging. “Plaque growth alone is not an indication or heart attacks and stroke,” he says. “Plaque growth may cause symptoms of angina [severe chest pain caused by an inadequate blood supply to the heart], but not necessarily events such as heart attacks that lead to death.”

Testosterone therapy should be initiated only after two morning total serum testosterone measurements show decreased levels, and all patients should be counseled on the potential risks and benefits before starting therapy. Potential benefits of therapy include increased libido, improved sexual function, improved mood and well-being, and increased muscle mass and bone density; however, there is little or mixed evidence confirming clinically significant benefits. The U.S. Food and Drug Administration warns that testosterone therapy may increase the risk of cardiovascular complications. Other possible risks include rising prostate-specific antigen levels, worsening lower urinary tract symptoms, polycythemia, and increased risk of venous thromboembolism.

You should start to see an increase in energy and stamina, as well as in your exercise capacity. Blood tests should also start to show better glycemic control and a decline in high blood pressure. In Month 3, working out and being active take less effort and yield quicker, more visible and dramatic results, thanks to better muscle healing and faster recovery. This leads to more substantial changes in body composition, such as increased muscle mass and decreasing body fat, as well as better overall physical strength.

Those in the testosterone group saw improvements in sexual function, mood and depression symptoms, bone mineral density and strength, and anemia. The bone improvements were in the trabecular bone, tissue found at the ends of long bones and in the pelvic bones, ribs, skull, and vertebrae in the spinal column. The treatment helped correct anemia, whether caused by low iron or an unidentifiable factor. The anemia “increases may be of clinical value…but the overall health benefits remain to be established,” the researchers write. Participants in the TTrials received a testosterone gel or placebo gel on the skin daily for one year.

Adverse effects specific to topical preparations include application site reactions (3-16% erythema or rash), and risk of transference. Patients should be particularly cautioned against contact with women and children after application of the gel to limit the possibility of inadvertent transmission. Transference may be mitigated by washing hands, covering the application site with clothing, and washing the region prior to anticipated direct contact with others. Given the mechanisms of action of anastrozole, clomiphene citrate, and hCG, patients using these medications should wait a longer period before follow-up blood work is performed.

Doctors will then repeat these tests annually if the results prove to be stable. A 2021 study suggests that long-term TRT improves liver function and reduces cardiovascular risks. However, further studies are needed to assess the long-term effects. However, doctors do not usually recommend TRT as the first course of action for low testosterone levels, even for males who show such symptoms. Also, some research shows that testosterone therapy can increase your risk of heart disease. Hormone therapy is often used alone for people who have a recurrence of prostate cancer after earlier treatment with radiation or surgery.